Detalles de la búsqueda
1.
Rac1 as a Potential Pharmacodynamic Biomarker for Thiopurine Therapy in Inflammatory Bowel Disease.
Ther Drug Monit;
38(5): 621-7, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27465973
2.
Clinical Value of Mercaptopurine After Failing Azathioprine Therapy in Patients With Inflammatory Bowel Disease.
Ther Drug Monit;
38(4): 463-70, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27158876
3.
Routinely Established Skewed Thiopurine Metabolism Leads to a Strikingly High Rate of Early Therapeutic Failure in Patients With Inflammatory Bowel Disease.
Ther Drug Monit;
37(6): 797-804, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25853923
4.
Exploring the role of oxidative stress and the effect of N-acetylcysteine in thiopurine-induced liver injury in inflammatory bowel disease: A randomized crossover pilot study.
Basic Clin Pharmacol Toxicol;
134(4): 507-518, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38284479
5.
Sustained clinical benefit and tolerability of methotrexate monotherapy after thiopurine therapy in patients with Crohn's disease.
Clin Gastroenterol Hepatol;
11(6): 667-72, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23333660
6.
Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease.
J Crohns Colitis;
17(5): 738-745, 2023 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36521000
7.
The continuous rediscovery and the benefit-risk ratio of thioguanine, a comprehensive review.
Expert Opin Drug Metab Toxicol;
16(2): 111-123, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-32090622
8.
PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease.
Am J Gastroenterol;
109(6): 925-7, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24896764
9.
Key insights from therapeutic drug monitoring in Crohn's disease patients.
Expert Opin Drug Metab Toxicol;
15(5): 399-406, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-30892105
10.
Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies.
Aliment Pharmacol Ther;
50(1): 54-65, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31094013
11.
Reply: To PMID 23333660.
Clin Gastroenterol Hepatol;
11(8): 1039, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23669208
12.
High inter-individual variability of serum xanthine oxidoreductase activity in IBD patients.
Nucleosides Nucleotides Nucleic Acids;
37(6): 317-323, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29723116
13.
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease.
Inflamm Bowel Dis;
24(12): 2606-2612, 2018 11 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-29788244
14.
Nodular Regenerative Hyperplasia of the Liver in Patients with IBD Treated with Allopurinol-Thiopurine Combination Therapy.
Inflamm Bowel Dis;
23(3): 448-452, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28151736
15.
Optimizing Thiopurine Therapy in Inflammatory Bowel Disease Among 2 Real-life Intercept Cohorts: Effect of Allopurinol Comedication?
Inflamm Bowel Dis;
23(11): 2011-2017, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28617756
16.
Rac Attack: Modulation of the Small GTPase Rac in Inflammatory Bowel Disease and Thiopurine Therapy.
Mol Diagn Ther;
20(6): 551-557, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27604084
17.
Nodular regenerative hyperplasia in inflammatory bowel disease patients with allopurinol-thiopurine cotherapy.
Eur J Gastroenterol Hepatol;
30(10): 1254-1255, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30063483
18.
Safety and effectiveness of long-term allopurinol-thiopurine maintenance treatment in inflammatory bowel disease.
Inflamm Bowel Dis;
19(2): 363-9, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22605661
19.
A plea for TDM-based optimisation for treatment of Crohn's disease.
Lancet Gastroenterol Hepatol;
2(2): 81, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28403990
20.
Hepatotoxicity associated with 6-methyl mercaptopurine formation during azathioprine and 6-mercaptopurine therapy does not occur on the short-term during 6-thioguanine therapy in IBD treatment.
J Crohns Colitis;
6(1): 95-101, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22261533